Seoul National University Bundang Hospital

6 articles published in JoVE

• Medicine

  
  Stabilized Longitudinal In Vivo Cellular-Level Visualization of the Pancreas in a Murine Model with a Pancreatic Intravital Imaging Window Inwon Park¹, Pilhan Kim^{2,3 1}Department of Emergency Medicine, Seoul National University Bundang Hospital, ²Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, ³KI for Health Science and Technology, Korea Advanced Institute of Science and Technology In vivo high-resolution imaging of the pancreas was facilitated with the pancreatic intravital imaging window.

• Medicine

  
  Virtual Prism Adaptation Therapy: Protocol for Validation in Healthy Adults Sungmin Cho*¹, Won-Seok Kim*², Seo Hyun Park², Jihong Park², Nam-Jong Paik^{2 1}Delvine Inc., ²Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital This experimental protocol demonstrates the use of virtual prism adaptation therapy (VPAT) in healthy adults and the association between VPAT and functional near infrared spectroscopy to determine the effect of VPAT on cortical activation. Results suggest that VPAT may be feasible and could induce similar behavioral adaptation as conventional prism adaptation therapy.

• Behavior

  
  Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation Yoon-Hee Choi^1,2, Nam-Jong Paik^{1 1}Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, ²Department of Physical Medicine and Rehabilitation, Soonchunhyang University College of Medicine, Soonchunhyang University Hospital Here, we present a protocol to develop and apply a mobile game-based virtual reality program for the recovery of upper limb dysfunction in patients with stroke. The present study shows that the mobile program is feasible and effectively promotes upper limb recovery in stroke patients.

• Medicine

  
  Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia Jin-Young Hwang¹, Hye-Min Sohn², Jin-Hee Kim², Seongjoo Park², Jin-Woo Park², Mi-Sun Lim², Sung-Hee Han^{2 1}Department of Anesthesiology and Pain Medicine, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, ²Department of Anesthesiology and Pain Medicine, SNU Bundang Hospital, Seongnamsi, Gyeonggido, Republic of Korea This study demonstrates the technique to make a minimally invasive and easily reproducible model of spinal cord ischemia in rats. Various degrees of hind limb motor deficit can be produced by controlling the aortic occlusion time.

• Cancer Research

  
  Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles Ji-Eun Chang¹, Hyun-Jong Cho², Sanghoon Jheon^{1,3 1}Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, ²College of Pharmacy, Kangwon National University, ³Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine Photodynamic therapy (PDT) is an alternative choice for lung cancer treatment. To increase the therapeutic effect of PDT, lung cancer-targeted nanoparticles combined with chemotherapy were developed. Both in vitro and in vivo anticancer efficacies of PDT with prepared nanoparticles were evaluated.

• Medicine

  
  Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs Seong Joon Ahn^1,2,3, Hye Kyoung Hong¹, Young Mi Na¹, Sang Jun Park^1,2, Jeeyun Ahn^1,2,4, Jaeseong Oh⁵, Jae Yong Chung⁶, Kyu Hyung Park^1,2, Se Joon Woo^{1,2 1}Department of Ophthalmology, Seoul National University Bundang Hospital, ²Department of Ophthalmology, College of Medicine, Seoul National University, ³Department of Ophthalmology, Hanyang University Hospital, ⁴Department of Ophthalmology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, ⁵Department of Clinical Pharmacology, Seoul National University Hospital, ⁶Department of Clinical Pharmacology, Seoul National University Bundang Hospital Rabbits are widely used to study the pharmacokinetics of intraocular drugs. We describe a method for conducting pharmacokinetic studies of intraocular drugs using rabbit eyes.