Korea Institute of Machinery and Materials 3 articles published in JoVE Bioengineering Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats In Gul Kim1, Yanru Wu2, Su A. Park3, Hana Cho1, Jung-Woog Shin2, Eun-Jae Chung1 1Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University, College of Medicine, 2Department of Biomedical Engineering, Inje University, Gimhae, 3Department of Nature-Inspired Nanoconvergence Systems, Korea Institute of Machinery and Materials Esophageal reconstruction is a challenging procedure, and development of a tissue-engineered esophagus that enables regeneration of esophageal mucosa and muscle and that can be implanted as an artificial graft is necessary. Here, we present our protocol to generate an artificial esophagus, including scaffold manufacturing, bioreactor cultivation, and various surgical techniques. Bioengineering Isokinetic Robotic Device to Improve Test-Retest and Inter-Rater Reliability for Stretch Reflex Measurements in Stroke Patients with Spasticity Minki Sin*1, Won-Seok Kim*2, Kyujin Cho3, Nam-Jong Paik2 1Department of Medical Assistant Robot, Daegu Research Center, Korea Institute of Machinery & Materials, 2Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 3School of Mechanical and Aerospace Engineering, Seoul National University/IAMD Using a robotic isokinetic device with electromyography (EMG) measurements, this protocol illustrates that isokinetic motion itself can improve inter-rater reliability for the angle of catch measurements in stroke patients with mild elbow flexor spasticity. Engineering Multiscale Structures Aggregated by Imprinted Nanofibers for Functional Surfaces Yeonho Jeong*1, Seok Kim*2, Nicholas Xuanlai Fang2, Seunghang Shin1, Hyunmin Choi1, Seonjun Kim1, Sin Kwon3, Young Tae Cho1 1Department of Mechanical Engineering, Changwon National University, 2Department of Mechanical Engineering, Massachusetts Institute of Technology, 3Printed Electronics Research Team, Korea Institute of Machinery and Materials Presented is an easy method to fabricate nano-micro multiscale structures, for functional surfaces, by aggregating nanofibers fabricated using an anodic aluminum oxide filter.
