Diagenode S.A. 1 article published in JoVE Biology Automating ChIP-seq Experiments to Generate Epigenetic Profiles on 10,000 HeLa Cells Geoffrey Berguet1, Jan Hendrickx1, Celine Sabatel1, Miklos Laczik1, Sharon Squazzo2, Ignacio Mazon Pelaez2, Rini Saxena2, Helene Pendeville1, Dominique Poncelet1 1Diagenode S.A., 2Diagenode Inc. Methods for mapping in vivo protein-DNA interactions are becoming crucial for every aspect of genomic research but they are laborious, costly, and time consuming. Here a commercially available robotic liquid handling system that automates chromatin immunoprecipitation for mapping in vivo protein-DNA interactions with limited amounts of cells is presented.
