IBM Research - Zurich 1 article published in JoVE Bioengineering Rapid Subtractive Patterning of Live Cell Layers with a Microfluidic Probe Aditya Kashyap1, Julien F. Cors1, Robert D. Lovchik1, Govind V. Kaigala1 1IBM Research - Zurich We present a protocol to perform subtractive patterning of live cell monolayers on a surface. This is achieved by local and selective lysis of adherent cells using a microfluidic probe (MFP). The cell lysate retrieved from local regions can be used for downstream analysis, enabling molecular profiling studies.
