Robert-Bosch-Hospital 1 article published in JoVE Medicine Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders Andreas Seitz1, Sascha Beck1, Valeria Martínez Pereyra1, Raffi Bekeredjian1, Udo Sechtem1, Peter Ong1 1Department of Cardiology and Angiology, Robert Bosch Hospital Coronary vasomotion disorders represent frequent functional causes of angina in patients with unobstructed coronaries. The underlying mechanism of angina (endotype) in these patients can be determined by a comprehensive invasive diagnostic procedure based on acetylcholine provocation testing followed by Doppler-derived assessment of the coronary flow reserve and microvascular resistance.
