Univ. Bordeaux 1 article published in JoVE Medicine Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease Néstor Pallares-Lupon1,2, Jason D. Bayer1,2, Bastien Guillot1,2, Guido Caluori1,2, Girish S. Ramlugun1,2, Kanchan Kulkarni1,2, Virginie Loyer1,2, Stephane Bloquet1,2, Dounia El Hamrani1,2, Jérôme Naulin1,2, Marion Constantin1,2, Pierre Dos Santos1,2,3, Olivier Bernus1,2, Pierre Jaïs1,2,3, Philippe Pasdois1,2, Richard D. Walton1,2 1Centre de recherche Cardio-Thoracique de Bordeaux, Univ. Bordeaux, 2IHU Liryc, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Univ., 3Electrophysiology and Ablation Unit, Bordeaux University Hospital (CHU) Here, we present a protocol to obtain high resolution micro computed tomography images of healthy and pathological large mammalian whole hearts with collagen-selective contrast enhancement.
