MRic, Univ Rennes 1 article published in JoVE Developmental Biology Targeted Laser Ablation in the Embryo of Saccharina latissima Samuel Boscq1, Stéphanie Dutertre2, Ioannis Theodorou1, Bénédicte Charrier1 1UMR8227, CNRS / Sorbonne University, 2Univ Rennes, CNRS, Inserm, Biosit UAR 3480 US_S 018, MRic Core Facility The destruction of specific cells in the embryo is a powerful tool for studying cellular interactions involved in cell fate. The present protocol describes techniques for the laser ablation of targeted cells in the early embryo of the brown alga Saccharina latissima.