Manchester Collaborative Centre for Inflammation Research 1 article published in JoVE Immunology and Infection Cultivation of Heligmosomoides Polygyrus: An Immunomodulatory Nematode Parasite and its Secreted Products Chris J. C. Johnston1, Elaine Robertson1, Yvonne Harcus1, John R. Grainger2, Gillian Coakley1, Danielle J. Smyth1, Henry J. McSorley1, Rick Maizels1 1Institute of Immunology and Infection Research, University of Edinburgh, 2Manchester Collaborative Centre for Inflammation Research Heligmosomoides polygyrus is a murine nematode with powerful immunomodulatory capabilities that closely resemble those of highly-prevalent human helminth infection. Here we describe a protocol for the long-term maintenance of the H. polygyrus lifecycle.
