AB Sciex UK Ltd 1 article published in JoVE Chemistry Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials Andrew J. Chetwynd*1, Wei Zhang*2, Klaus Faserl*3, James A. Thorn4, Iseult Lynch1, Rawi Ramautar2, Herbert H. Lindner3 1School of Geography Earth and Environmental Sciences, University of Birmingham, 2Biomedical Microscale Analytics, Leiden University, 3Institute of Medical Biochemistry, Medical University of Innsbruck, 4AB Sciex UK Ltd Here we present a protocol to characterize the complete biomolecular corona, proteins, and metabolites, acquired by nanomaterials from biofluids using a capillary electrophoresis – mass spectrometry approach.
