University of Pecs 1 article published in JoVE Medicine Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs Gábor B Brenner*1,2, Zoltán Giricz*1,2, Rita Garamvölgyi3,4, András Makkos1, Zsófia Onódi1, Nabil V Sayour1, Tamás G Gergely1, Tamás Baranyai1, Örs Petneházy3,4, Dénes Kőrösi3, Gergő P. Szabó3, Hajnalka Vago5, Zsófia Dohy5, Csilla Czimbalmos5, Béla Merkely5, Swetlana Boldin-Adamsky6, Elena Feinstein6, Iván G Horváth7, Péter Ferdinandy1,2 1Department of Pharmacology and Pharmacotherapy, Semmelweis University, 2Pharmahungary Group, 3Diagnostic, Radiation Oncology, Research and Teaching Center, Moritz Kaposi Somogy County Teaching Hospital, 4Faculty of Agricultural and Environmental Sciences, Kaposvar University, 5Heart and Vascular Center, Semmelweis University, 6Quark Pharmaceuticals, Inc, 7Heart Institute, Medical School, University of Pécs The overall goal of the current study is to present the techniques of induction of myocardial infarction (MI) and post-myocardial infarction heart failure (post-MI HF) in closed-chest, adult Göttingen minipigs and the characterization of post-MI HF model in Göttingen minipigs as compared to Landrace pigs.
