Core Research Laboratory, ISPRO 1 article published in JoVE Cancer Research Analysis of Lymph Node Volume by Ultra-High-Frequency Ultrasound Imaging in the Braf/Pten Genetically Engineered Mouse Model of Melanoma Marianna Vitiello1,2, Claudia Kusmic1, Francesco Faita1, Laura Poliseno1,2 1Institute of Clinical Physiology, National Research Council (IFC-CNR), 2Oncogenomics Unit, Core Research Laboratory, ISPRO Melanoma is a very aggressive disease that quickly spreads to other organs. This protocol describes the application of ultra-high-frequency ultrasound imaging, coupled with 3D rendering, to monitor the volume of the inguinal lymph nodes in the Braf/Pten mouse model of metastatic melanoma.
