BioPharmaceuticals R and D

1 article published in JoVE

• Medicine

  
  Direct Drug Delivery to Kidney via the Renal Artery Ulrika Dahlqvist¹, Tajana Tesan Tomic², Magnus Söderberg³, Jane Stubbe⁴, Camilla Enggaard⁴, Anette Ericsson⁵, Alex-Xianghua Zhou¹, Anna Björnson Granqvist¹, Lena William-Olsson^{1 1}Bioscience Renal, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, ²Cell/mol Pharmacology, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, ³CVRM Safety, Safety, Clinical Pharmacology & Safety Sciences, R&D, ⁴Department of Cardiovascular and Renal Research, University of Southern Denmark, ⁵Clinical Renal, Late-stage Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D This manuscript describes a method for targeted delivery to a single kidney via a catheter placed in the infrarenal abdominal aorta in the mouse.