2 articles published in JoVE
An Objective and Child-friendly Assessment of Arm Function by Using a 3-D Sensor Xing Chen1, Detlef Wolf1, Juliane Siebourg-Polster2, Christian Czech3, Ulrike Bonati4,5, Dirk Fischer4,5, Omar Khwaja6, Martin Strahm1 1Data Science, Roche Pharmaceutical Research and Early Development Informatics, Roche Innovation Center Basel, F. Hoffmann-La Roche, Ltd., 2Translational Technologies and Bioinformatics, Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche, Ltd., 3Biomarker Experimental Medicine, Neuroscience, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche, Ltd., 4 An objective measure of muscle functions is challenging especially in children. Based on a commercially available digital 3-D sensor, a child-friendly gaming test was developed to assess upper limb function for clinical trials.
Electrophysiological Measurement of Noxious-evoked Brain Activity in Neonates Using a Flat-tip Probe Coupled to Electroencephalography Noemi Klarer*1, Hanna Rickenbacher*1, Severin Kasser1, Antoinette Depoorter2, Sven Wellmann1 1 Measuring pain in non-verbal patients is a challenge. In this study we combine EEG recording with stimulation using a flat-tip probe to detect noxious-evoked brain activity in an objective manner.