3 articles published in JoVE
A Method for Determination and Simulation of Permeability and Diffusion in a 3D Tissue Model in a Membrane Insert System for Multi-well Plates Hao-Hsiang Hsu1, John-Kevin Kracht1, Laura Elisabeth Harder1, Kerstin Rudnik1, Gerd Lindner2, Katharina Schimek2, Uwe Marx3, Ralf Pörtner1 1Institute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, 2Institute of Biotechnology, Department Medical Biotechnology, Technische Universität Berlin, 3TissUse GmbH A method for determination of permeability in a membrane insert system for multi-well plates and in silico parameter optimization for the calculation of diffusion coefficients using simulation are presented.
Preparation of Biopolymer Aerogels Using Green Solvents Raman Subrahmanyam1, Pavel Gurikov1, Imke Meissner1, Irina Smirnova1 1Institute of Thermal Separation Processes, Hamburg University of Technology A new way for the production of biopolymer-based aerogels by carbon dioxide (CO2) induced gelation is shown. The technique utilizes pressurized carbon dioxide (5 MPa) for the production of biopolymer hydrogels and supercritical CO2 (12 MPa) to convert gels into aerogels. The only solvents needed besides CO2 are water and ethanol.
Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion Nicole Brazda*1, Veronica Estrada*1, Christian Voss2,3, Klaus Seide3, Hoc Khiem Trieu2, Hans Werner Müller1 1Molecular Neurobiology Laboratory, Department of Neurology, Heinrich-Heine-University Medical Center, 2Institute of Microsystems Technology, Hamburg University of Technology, 3Biomechanical Laboratory, BG Trauma Center Hamburg Severe spinal cord injuries often result in tissue defects. Two possibilities are described to successfully bridge such gaps to promote tissue adaptation, regenerative responses and functional improvement in rats via implantation of a mechanical microconnector system after acute injury and five weeks after complete spinal cord transection.