KIST Europe Forschungsgesellschaft mbH 1 article published in JoVE Bioengineering In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox Marie-Léonie Bohlen1, Hyun Pyo Jeon1, Young Jun Kim1, Baeckkyoung Sung1 1KIST Europe Forschungsgesellschaft mbH Quantitative structure-activity relationship (QSAR) modeling is a representative bioinformatics-assisted method in toxicological screening. This protocol demonstrates how to computationally assess the risks of endocrine disruptors (EDs) in aquatic environments. Utilizing the OECD QSAR Toolbox, the protocol implements an in silico assay for analyzing toxicity of EDs in fish.
