Universite Rene Descartes 1 article published in JoVE Medicine A New Murine Model of Endovascular Aortic Aneurysm Repair Martin Rouer1, Olivier Meilhac1, Sandrine Delbosc1, Liliane Louedec1, Graciela Pavon-Djavid1,2, Jane Cross3, Josette Legagneux4, Maxime Bouilliant-Linet4, Jean-Baptiste Michel1, Jean-Marc Alsac1,5 1INSERM U698 Cardiovascular Remodelling, Hôpital X. Bichat, AP-HP, Paris, 2Bio-Ingénierie des Polymères Cardiovasculaires (BPC), Institut Galilée - Université Paris 13, Paris, France, 3Service de Chirurgie Vasculaire, Hôpital Henri Mondor, AP-HP, Université Paris-Est Creteil, 4 Histological and biochemical modifications after aneurysm endograft exclusion are still unclear. We describe a new model of endograft implantation on a murine aneurysm. Through thrombus analysis with and without persistant circulating blood stream interface, and new endovascular biomaterials evaluation, this model will help to better understand endovascular aneurysm exclusion pathobiology.
