Experimentica Ltd. 2 articles published in JoVE Medicine Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents Maria Vähätupa1,2, Niina Jääskeläinen2, Marc Cerrada-Gimenez2, Rubina Thapa2, Tero Järvinen1, Giedrius Kalesnykas2, Hannele Uusitalo-Järvinen1,3 1Faculty of Medicine and Health Technology, Tampere University & Tampere University Hospital, 2Experimentica Ltd, 3Eye Centre, Tampere University Hospital Oxygen-induced retinopathy (OIR) can be used to model ischemic retinal diseases such as retinopathy of prematurity and proliferative diabetic retinopathy and to serve as a model for proof-of-concept studies in evaluating antiangiogenic drugs for neovascular diseases. OIR induces robust and reproducible neovascularization in the retina that can be quantified. Neuroscience In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model Symantas Ragauskas1, Eva Kielczewski2, Joseph Vance2,3, Simon Kaja1,4, Giedrius Kalesnykas1 1Experimentica Ltd., 2Leica Microsystems, 3Spective LLC, 4Department of Ophthalmology, Stritch School of Medicine, Loyola University Chicago Here, we present the usefulness of longitudinal in vivo imaging in the follow-up of morphological changes of laser-induced choroidal neovascularization in mice.
