Aalto University School of Science 3 articles published in JoVE Medicine Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping Pantelis Lioumis1,2, Salla Autti1,2, Juha Wilenius2,3, Selja Vaalto1,2,3, Henri Lehtinen3,5, Aki Laakso4, Erika Kirveskari3, Jyrki P. Mäkelä2, Mia Liljeström1,2, Hanna Renvall1,2 1Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, 2BioMag Laboratory, HUS Diagnostic Center, University of Helsinki, Aalto University, and Helsinki University Hospital, 3Department of Clinical Neurophysiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, 4Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, 5Department of Child Neurology, University of Helsinki and Helsinki University Hospital Navigated repetitive transcranial magnetic stimulation is a highly efficient non-invasive tool for mapping speech-related cortical areas. It helps in designing brain surgery and speeds up the direct cortical stimulation conducted during the surgery. This report describes how to perform speech cortical mapping reliably for preoperative evaluation and research. Neuroscience Measuring Properties of the Membrane Periodic Skeleton of the Axon Initial Segment using 3D-Structured Illumination Microscopy (3D-SIM) David Micinski1, Lauri Lahti2, Amr Abouelezz1,3,4 1Minerva Foundation Institute for Medical Research, 2Department of Computer Science, Aalto University School of Science, 3HiLIFE - Neuroscience Center, University of Helsinki, 4HiLIFE - Institute of Biotechnology, University of Helsinki The present protocol describes a method to visualize and measure actin rings and other components of the membrane periodic skeleton of the axon initial segment using cultured rat hippocampal neurons and 3D-structured illumination microscopy (3D-SIM). Chemistry Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates Yike Huang1, Minh-Kha Nguyen1,2, Anton Kuzyk1 1Department of Neuroscience and Biomedical Engineering, Aalto University School of Science, Aalto FI-00076, 2Faculty of Chemical Engineering, Ho Chi Minh City (HCMC) University of Technology, Vietnam National University - Ho Chi Minh City (VNU-HCM), Ho Chi Minh City 700000 We describe the detailed protocol for the DNA origami-based assembly of gold nanorods into chiral plasmonic metamolecules with strong chiroptical responses. The protocol is not limited to chiral configurations and can be easily adapted for the fabrication of various plasmonic architectures.
