CYTOO Cell Architects View Institution's Website 1 article published in JoVE Bioengineering Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells Sébastien Degot1, Muriel Auzan1, Violaine Chapuis1, Anne Béghin2, Amélie Chadeyras1, Constantin Nelep1, Maria Luisa Calvo-Muñoz1, Joanne Young1, François Chatelain1, Alexandra Fuchs1 1CYTOO Cell Architects, Grenoble, France, 2Centre Commun de Quantimétrie, Faculté de Médecine Rockefeller, Lyon, France Adhesive micropatterns that normalize cellular architecture can be used to increase sensitivity in the detection of drug effects, improve reproducibility and simplify automated image acquisition and analysis. Such technology will benefit drug/siRNA screening assays, performed on conventional cell culture supports and consequently suffering from excessive cell-to-cell variability.
