Universite de Corte Pascal Paoli 1 article published in JoVE Biology A Capsule-Based Model for Immature Hard Tick Stages Infestation on Laboratory Mice Lourdes Mateos-Hernández1, Sabine Rakotobe1, Baptiste Defaye1,2,3, Alejandro Cabezas-Cruz1, Ladislav Šimo1 1UMR BIPAR, INRAE, Ecole Nationale Vétérinaire d'Alfort, ANSES, Université Paris-Est, 2Faculté de Pharmacie, Université de Limoges, 3UMR SPE 6134 CNRS, Université de Corte Pascal Paoli In this study, a feeding system for nymphal and larval stages of hard tick was developed using a capsule attached to laboratory mouse. The feeding capsule is made from flexible materials and remains firmly attached to the mouse for at least one week and allows comfortable monitoring of tick feeding.