University Hospital of Wales 1 article published in JoVE Bioengineering Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction Christopher D. Roche1,2,3,4, Carmine Gentile1,2,3 1The University of Sydney, 2University of Technology Sydney (UTS), 3The Royal North Shore Hospital, 4University Hospital of Wales This protocol aims to transplant a 3D bioprinted patch onto the epicardium of infarcted mice modeling heart failure. It includes details regarding anesthesia, the surgical chest opening, permanent ligation of the left anterior descending (LAD) coronary artery and application of a bioprinted patch onto the infarcted area of the heart.
