2 articles published in JoVE
Comparative Lesions Analysis Through a Targeted Sequencing Approach Caterina Vicentini1, Andrea Mafficini1, Michele Simbolo2, Matteo Fassan3, Pietro Delfino2, Rita Teresa Lawlor1, Borislav Rusev1, Aldo Scarpa1,2, Vincenzo Corbo1,2 1ARC-Net Research Centre, University and Hospital Trust of Verona, 2Department of Diagnostics and Public Health, Section of Pathology, University and Hospital Trust of Verona, 3Department of Medicine (DIMED), Surgical Pathology and Cytopathology Unit, University of Padua This article describes a method to identify clonal and subclonal alterations among different specimens from a given patient. Although the experiments described here focus on a specific tumor type, the approach is broadly applicable to other solid tumors.
Laparoscopic Pancreatoduodenectomy With Modified Blumgart Pancreaticojejunostomy Matteo De Pastena1,2, Jony van Hilst1, Thijs de Rooij1, Olivier R Busch1, Michael F Gerhards3, Sebastiaan Festen3, Marc G Besselink1 1Department of Surgery, Cancer Center Amsterdam, Academic Medical Center, 2General and Pancreatic Surgery Department, Pancreas Institute, University and Hospital Trust of Verona, 3Department of Surgery, OLVG Laparoscopic pancreatoduodenctomy (LPD) may offer advantages over open pancreatoduodenectomy, including early postoperative mobilization, less delayed gastric emptying and a shorter hospital stay. However, LPD is technically challenging and not well-standardized, especially regarding the pancreatic anastomosis. We describe a standardized technique for the pancreatic anastomosis during LPD: modified Blumgart pancreaticojejunostomy.