Golgi-Cenci Foundation 1 article published in JoVE Neuroscience Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains Tino Emanuele Poloni*1,4, Valentina Medici*1, Arenn Faye Carlos1, Annalisa Davin2, Arcangelo Ceretti1, Michela Mangieri1, Paola Cassini1,4, Roberta Vaccaro3, Daniele Zaccaria3, Simona Abbondanza3, Matteo Bordoni5, Valentina Fantini2,6, Elena Fogato7, Cristina Cereda5, Mauro Ceroni8, Antonio Guaita1,2,3 1Department of Neurology and Neuropathology, Golgi-Cenci Foundation, 2Laboratory of Neurobiology and Neurogenetic, Golgi-Cenci Foundation, 3Department of Neuropsychology and Social Sciences, Golgi-Cenci Foundation, 4Department of Rehabilitation, ASP Golgi-Redaelli Geriatric Hospital, 5Genomic and Post-Genomic Center, IRCCS Mondino Foundation, 6Department of Brain and Behavioral Sciences, University of Pavia, 7Department of Pathology, ASP Golgi-Redaelli Geriatric Hospital, 8Department of Neurological Science, IRCCS Mondino Foundation, University of Pavia This protocol describes a method to track individual brain-aging trajectories through a brain donation program and proper characterization of brains. Brain donors are involved in a long-term longitudinal study including serial multi-dimensional assessments. The protocol contains a detailed description of brain processing and an accurate diagnostic methodology.
