3 articles published in JoVE
Diffuse Reflectance Spectroscopy: Getting the Capillary Refill Test Under One's Thumb Joakim Henricson1,2, Rani Toll John1,3, Chris D. Anderson4,5, Daniel Björk Wilhelms1,2 1Department of Emergency Medicine, Local Health Care Services in Central Östergötland, Region Östergötland, 2Division of Drug Research, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, 3Division of Neuro and Inflammation Science, Department of Clinical and Experimental Medicine, Linköping University, 4Division of Cell Biology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, 5Department of Dermatology and Venerology, Heart and Medicine Center, Region Östergötland This protocol describes how the use of diffuse polarization spectroscopy can improve the clinical usefulness of the capillary refill test. We suggest a more detailed analysis of the course of the capillary refill in healthy volunteers using diffuse reflectance spectroscopy videos and new informatic endpoints.
Imaging Amyloid Tissues Stained with Luminescent Conjugated Oligothiophenes by Hyperspectral Confocal Microscopy and Fluorescence Lifetime Imaging Sofie Nyström1, Marcus Bäck1, K. Peter R. Nilsson1, Per Hammarström1 1IFM-Department of Chemistry, Linköping University Amyloid deposition is a hallmark of different diseases and afflicts many different organs. This paper describes the application of luminescent conjugated oligothiophene fluorescence staining in combination with fluorescence microscopy techniques. This staining method represents a powerful tool for detection and exploration of protein aggregates in both clinical and scientific setups.
Ovariectomy and 17β-estradiol Replacement in Rats and Mice: A Visual Demonstration Jakob O. Ström1, Annette Theodorsson1, Edvin Ingberg1, Ida-Maria Isaksson1, Elvar Theodorsson1 1Clinical Chemistry and Neurosurgery, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University Ovariectomy and subsequent replacement of 17β-estradiol by means of silastic capsules and peroral Nutella are demonstrated in rats and mice.