Applied Research Associates, Inc. 1 article published in JoVE Behavior Noninvasive, In-pen Approach Test for Laboratory-housed Pigs Lindsey E. Hulbert1, Eduarda M. Bortoluzzi1, Yunzhi Luo1, Jared M. Mumm1, Morgan J. Coffin1, Gina Y. Becker2, Pamela J. Vandevord3, Elizabeth M. McNeil3, Tim Walilko4, Zin Z. Khaing5,6, Laila Zai4,5 1Animal Sciences and Industry, Kansas State University, 2DynaSim Technical Services, INC, 3Center for Injury Biomechanics, Virginia Polytechnic Institute and State University, 4Applied Research Associates, Inc., 5Lucent Research, LLC, 6Department of Neurological Surgery, University of Washington This protocol describes a new behavioral test—the human approach test in the pigs' home pen—to detect functional deficits in laboratory pigs after subconcussive traumatic brain injury.