Wilkes Honors College and Florida Atlantic University 1 article published in JoVE Behavior Behavioral Approaches to Studying Innate Stress in Zebrafish Jacqueline S.R. Chin1, Lydia T. Albert2, Cody L. Loomis1,3, Alex C. Keene1,3, Erik R. Duboué1,2,3 1Jupiter Life Science Initiative, Florida Atlantic University, 2Wilkes Honors College and Florida Atlantic University, 3Charles E. Schmidt College of Science, Florida Atlantic University This manuscript describes a simple method to measure stress behaviorally in adult zebrafish. The approach takes advantage of the innate tendency that zebrafish prefer the bottom half of a tank when in a stressful state. We also describe methods for coupling the assay with pharmacology.
