Florida Atlantic University, John D. MacArthur Campus 1 article published in JoVE Behavior Swimming Induced Paralysis to Assess Dopamine Signaling in Caenorhabditis elegans Sirisha Kudumala1, Serena Sossi2, Lucia Carvelli1,3,4 1Harriet Wilkes Honors College, Florida Atlantic University, John D MacArthur Campus, 2Integrative Biology and Neuroscience program, College of Science, Florida Atlantic University, 3Brain Institute, Florida Atlantic University, 4Department of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University Swimming induced paralysis (SWIP) is a well-established behavioral assay used to study the underlying mechanisms of dopamine signaling in Caenorhabditis elegans (C. elegans). However, a detailed method to perform the assay is lacking. Here, we describe a step-by-step protocol for SWIP.
