Veterans Affairs Boston Healthcare System 3 articles published in JoVE Cancer Research Venous Thrombosis Assay in a Mouse Model of Cancer Saran Lotfollahzadeh1, Xiaosheng Yang1, David Jasen Wu Wong1, Jingyan Han2, Francesca Seta2, Suvranu Ganguli3, Asha Jose1, Katya Ravid4,5, Vipul C. Chitalia1,6,7,8 1Renal Section, Department of Medicine, Chobanian and Avedisian School of Medicine, Boston University, 2Vascular Biology Section, Department of Medicine, Chobanian and Avedisian School of Medicine, Boston University, 3Division of Interventional Radiology, Department of Radiology, Chobanian and Avedisian School of Medicine, Boston University, 4Department of Medicine, Whitaker Cardiovascular Institute, Chobanian and Avedisian School of Medicine, Boston University, 5Department of Biochemistry and Cell Biology, Chobanian and Avedisian School of Medicine, Boston University, 6Veterans Affairs Boston Healthcare System, 7Institute of Medical Engineering and Sciences, Massachusetts Institute of Technology, 8Center of Cross-Organ Vascular Pathology, Department of Medicine, Chobanian and Avedisian School of Medicine, Boston University This article aims to present an optimized method for assessing venous thrombosis in a mouse cancer model, using vascular clips to achieve venous ligation. Optimization minimizes variability in thrombosis-related measurements and enhances relevance to human cancer-associated venous thrombosis. Medicine A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice Saran Lotfollahzadeh1, Mengwei Zhang1, Marc Arthur Napoleon1, Wenqing Yin1, Josephine Orrick1, Nagla Elzind1, Austin Morrissey1, Isaac E. Sellinger1, Lauren D. Stern1, Mostafa Belghasem2, Jean M. Francis1, Vipul C. Chitalia1,3,4 1Renal Section, Department of Medicine, Boston University Aram V. Chobanian & Edward Avedisian School of Medicine, 2Department of Biomedical Science, Kaiser Permanente Bernard J. Tyson School of Medicine, 3Veterans Affairs Boston Healthcare System, 4Institute of Medical Engineering and Sciences, Massachusetts Institute of Technology This article describes modifications of a procedure to implant a peritoneal dialysis catheter in a murine model to avoid major technical issues observed with the conventional techniques. Medicine Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia Gabriella Garcia1,2, Catherine Norise1,2, Olufunsho Faseyitan1,2, Margaret A. Naeser3,4,5, Roy H. Hamilton1,2 1Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 2Center for Cognitive Neuroscience, University of Pennsylvania, 3Veterans Affairs Boston Healthcare System, 4Harold Goodglass Aphasia Research Center, Boston University School of Medicine, 5Department of Neurology, Boston University School of Medicine We explore the use of repetitive transcranial magnetic stimulation (rTMS) to improve language abilities in patients with chronic stroke and non-fluent aphasia. After identifying a site in the right frontal gyrus for each patient that responds optimally to stimulation, we target this site during ten days of rTMS treatment.
