Mayo Clinic College of Medicine, Mayo Clinic Cancer Center 1 article published in JoVE Cancer Research Zebrafish Model of Neuroblastoma Metastasis Zuag Paj Her1, Kok Siong Yeo1, Cassie Howe1, Taylor Levee1, Shizhen Zhu1 1Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center This paper introduces the method of developing, characterizing, and tracking in real-time the tumor metastasis in zebrafish model of neuroblastoma, specifically in the transgenic zebrafish line with overexpression of MYCN and LMO1, which develops metastasis spontaneously.
