Texas A&M Institute for Genomic Medicine 1 article published in JoVE Immunology and Infection A Murine Pancreatic Islet Cell-based Screening for Diabetogenic Environmental Chemicals Jingshu Chen*2, Lei Zhong*1, Jing Wu1, Sui Ke2, Benjamin Morpurgo3, Andrei Golovko3, Nengtai Ouyang4, Yuxiang Sun2, Shaodong Guo2, Yanan Tian1,2 1Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, Hunan Agriculture University, 2Texas A&M University, 3Texas A&M Institute for Genomic Medicine, 4Sun Yat-Sen Memorial Hospital Here we present a protocol to isolate mouse pancreatic islet cells for screening the ROS inductions by the xenobiotics in order to identify the potential diabetogenic xenobiotic chemicals.
