West Virginia School of Osteopathic Medicine 2 articles published in JoVE Biology A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats Sarai B. Arbus1, John M. Pirtle1, Christopher L. Pankey1 1West Virginia School of Osteopathic Medicine This paper presents the morphometric responses and training performance outcomes of a high-intensity interval training (HIIT) protocol in a Sprague-Dawley rat model of diet-induced obesity. The purpose of this protocol was to maximize exercise intensity and determine the physiologic responses to HIIT in lean and obese rats. Behavior Utilizing the Modified T-Maze to Assess Functional Memory Outcomes After Cardiac Arrest Celeste Y. C. Wu1,2, Francesca M. Lerner4, Alexandre Couto e Silva3, Harlee E. Possoit1,2, Tsung-Han Hsieh1,2, Jake T. Neumann5, Alireza Minagar1, Hung Wen Lin1,2,3, Reggie H. C. Lee1,2 1Department of Neurology, Louisiana State University Health Science Center, 2Center for Brain Health, Louisiana State University Health Science Center, 3Department of Cellular Biology and Anatomy, Louisiana State University Health Science Center, 4Department of Neurology, Cerebral Vascular Disease Research Laboratories, University of Miami Miller School of Medicine, 5Department of Biomedical Sciences, West Virginia School of Osteopathic Medicine This protocol describes the use of a modified T-maze to evaluate functional learning/memory in asphyxia cardiac arrest-induced cerebral ischemia.
