2 articles published in JoVE
Sagittal Plane Kinematic Gait Analysis in C57BL/6 Mice Subjected to MOG35-55 Induced Experimental Autoimmune Encephalomyelitis Maximillian DJ Fiander*1, Matthew AJ Chedrawe*1, Anna-Claire Lamport1, Turgay Akay2, George S Robertson1,3 1Pharmacology, Dalhousie University, 2Medical Neuroscience, Dalhousie University, 3Psychiatry, Dalhousie University Kinematic gait analysis in the sagittal plane yields highly precise information about how movement is executed. We describe the application of these techniques to identify gait deficits for mice subjected to autoimmune-mediated demyelination. These methods may also be used to characterize gait deficits for other mouse models featuring impaired locomotion.
Horizontal Slice Preparation of the Retina Ryosuke Enoki1, Tatjana C. Jakobs2, Amane Koizumi2 1Dpt of Physiology and Biophysics, Dalhousie University, 2Massachusetts General Hospital, Harvard Medical School Traditionally the vertical slice and the whole-mount preparation of the retina have been used to study the function of retinal circuits. Here, we describe the novel slicing method to preserve the dendritic morphology of retinal neurons intact.