National Autonomous University of Mexico

5 articles published in JoVE

• Neuroscience

  
  How to Obtain Reliable Visual Event-related Potentials in Newborns Lourdes Cubero-Rego¹, Josefina Ricardo-Garcell¹, Thalía Harmony¹, María Corsi-Cabrera^{1,2 1}Research Unit in Neurodevelopment, Institute of Neurobiology, National Autonomous University of Mexico, ²Sleep Laboratory, Faculty of Psychology, National Autonomous University of Mexico Several important points for obtaining high-quality reliable visual evoked potentials (VEPs) in newborns while minimizing variability and the risk of misleading prognoses are presented.

• Chemistry

  
  Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness Josué Arenas-García¹, Martha V. Escárcega-Bobadilla², Gustavo A. Zelada-Guillén^{1 1}Department of Analytical Chemistry, School of Chemistry, National Autonomous University of Mexico, ²Department of Organic Chemistry, School of Chemistry, National Autonomous University of Mexico A procedure for the synthesis of polystyrene-grafted multiwalled carbon nanotubes using successive chemical modification steps to selectively introduce the polymer chains to the sidewalls and their self-assembly via anisotropic patchiness is presented.

• Behavior

  
  fMRI Mapping of Brain Activity Associated with the Vocal Production of Consonant and Dissonant Intervals Nadia González-García¹, Pablo L. Rendón^{2 1} The neural correlates of listening to consonant and dissonant intervals have been widely studied, but the neural mechanisms associated with production of consonant and dissonant intervals are less well known. In this article, behavioral tests and fMRI are combined with interval identification and singing tasks to describe these mechanisms.

• Immunology and Infection

  
  In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis Nohemi Salinas-Jazmín^1,2, Edith González-González¹, Luz X. Vásquez-Bochm³, Sonia M. Pérez-Tapia^4,5, Marco A. Velasco-Velázquez^{6 1}Unit for Development and Research in Bioprocesses Unit (UDIBI), National School of Biological Sciences, National Polytechnic Institute (IPN), University of Mexico (UNAM), ²School of Chemistry, National Autonomous University of Mexico (UNAM), ³Graduate Program in Chemical Sciences, National Autonomous University of Mexico (UNAM), ⁴Unit for Development Research and Medical Innovation in Biotechnology (UDIMEB), National School of Biological Sciences, National Polytechnic Institute (IPN), ⁵Department of Immunology, National Scool of Biological Sciences, National Polytechnic Institute (IPN), ⁶Department of Pharmacology and Unit of Translational Biomedicine (CMN 20 de noviembre), School of Medicine, National Autonomous University of Mexico (UNAM) This protocol describes the in vitro comparison of two key functional characteristics of rituximab: target binding and complement-dependent cytotoxicity (CDC) induction. The methods were employed for a side-to-side comparison between reference rituximab and a rituximab biosimilar. These assays can be employed during biosimilar development or as a quality control in their production.

• Chemistry

  
  HKUST-1 as a Heterogeneous Catalyst for the Synthesis of Vanillin Rebeca Yépez¹, Juan F. Illescas¹, Paulina Gijón¹, Manuel Sánchez-Sánchez², Eduardo González-Zamora³, Rosa Santillan⁴, J. Raziel Álvarez⁵, Ilich A. Ibarra⁵, Julia Aguilar-Pliego^{1 1}Autonomous Metropolitan University-Azcapotzalco, ²Institute of Catalysis and Petroleum Chemistry, ICP-CSIC, ³Department of Chemistry, Autonomous Metropolitan University-Iztapalapa, ⁴Department of Chemistry, Center of Investigation and Superior Studies (IPN), ⁵Research Institute of Material, National Autonomous University of Mexico The conversion of trans-ferulic acid to vanillin was achieved by heterogeneous catalysis. HKUST-1 was employed in this synthesis and the essential step in the catalytic process was the generation of unsaturated metal sites. Thus, when the catalyst was activated under vacuum, full vanillin conversion (yield of 95%) was obtained.