Ovation Fertility 1 article published in JoVE Developmental Biology Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts Mitchel C. Schiewe1, Shane Zozula1, Nancy Nugent1, Kelley Waggoner1, Jessica Borba1, Lisa Gamboa1, John B. Whitney1 1Ovation Fertility MicroSecure Vitrification was developed as a non-commercial, aseptic closed vitrification device system that is compliant with FDA good manufacturing and tissue-handling practices. Due to the withdrawal of hydrophobic plugged embryo straws from the industry, the vitrification procedure was modified to include an inner seal before the standard internal cotton plug.