2 articles published in JoVE
Collecting Hair Samples for Hair Cortisol Analysis in African Americans Kathy D. Wright1, Jodi L. Ford1, Joseph Perazzo2, Lenette M. Jones3, Sherrilynn Mahari4, Brent A. Sullenbarger5,6,7, Mark L. Laudenslager8 1College of Nursing, The Ohio State University, 2College of Nursing, University of Cincinnati, 3School of Nursing, University of Michigan, 4Licensed Cosmetologist Consultant, 5Clinical Research Manager, The Ohio State University, 6Biomedical Core Research Coordinator, The Ohio State University, 7College of Nursing Biomedical Core Research Laboratory, The Ohio State University, 8Department of Psychiatry, Behavioral Immunology & Endocrinology Laboratory, University of Colorado Denver Anschutz Medical Campus Hair cortisol concentration analysis provides an alternative to traditional measures of cortisol; however, to collect hair samples from African Americans, scientists need to be culturally informed and competent. The purpose of this protocol is to demonstrate a culturally informed technique to collect hair samples for cortisol analysis from African Americans.
Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies Stacey Bagby1, Wells A. Messersmith1, Todd M. Pitts1, Anna Capasso1, Marileila Varella-Garcia1, Peter J. Klauck1, Jihye Kim1, Aik-Choon Tan1, S. Gail Eckhardt1, John J. Tentler1, John Arcaroli1 1Medicine, University of Colorado Denver Anschutz Medical Campus Utilizing patient-derived tumors in a subcutaneous preclinical model is an excellent way to study the efficacy of novel therapies, predictive biomarker discovery, and drug resistant pathways. This model, in the drug development process, is essential in determining the fate of many novel anti-cancer therapies prior to clinical investigation.