3 articles published in JoVE
Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides Ruben Neves1, Kailyn Stephens1, Jillian E. Smith-Carpenter1 1Department of Chemistry and Biochemistry, Fairfield University A protocol for the synthesis of a 1,2-dithiolane modified peptide and the characterization of the supramolecular structures resulting from the peptide self-assembly.
Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity Amanda S. Harper-Leatherman1, Elizabeth R. Pacer1, Nina D. Kosciuszek1 1Department of Chemistry & Biochemistry, Fairfield University This procedure describes how to encapsulate cytochrome c (cyt. c) in silica (SiO2) sol-gels, process these gels to form bioaerogels, and use these bioaerogels to rapidly recognize nitric oxide (NO) through a gas-phase reaction. This type of protocol may aid in the future development of biosensors or other bioanalytical devices.
Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction C. R. Gallistel1, Fuat Balci1,2, David Freestone1,3, Aaron Kheifets1, Adam King4 1Department of Psychology, Rutgers University, 2Department of Psychology, Koç University, 3Center for Neural Science, New York University, 4Department of Mathematics & Computer Science, Fairfield University Fully automated system for measuring physiologically meaningful properties of the mechanisms mediating spatial localization, temporal localization, duration, rate and probability estimation, risk assessment, impulsivity, and the accuracy and precision of memory, in order to assess the effects of genetic and pharmacological manipulations on foundational mechanisms of cognition in mice.