Kent Scientific Corporation 2 articles published in JoVE Medicine Use of an Integrated Low-Flow Anesthetic Vaporizer, Ventilator, and Physiological Monitoring System for Rodents Krista Bigiarelli1, Luke E. Schepers2, Arvin H. Soepriatna2, Dave FitzMiller3, Craig J. Goergen2 1Pre-Clinical Research and Development, Kent Scientific Corporation, 2Weldon School of Biomedical Engineering, Purdue University, 3Marketing Research and Development, Kent Scientific Corporation Here, we present a protocol to safely and effectively administer anesthetic gas to mice using a digital, low flow anesthesia system with integrated ventilator and physiological monitoring modules. Medicine Use of a Low-flow Digital Anesthesia System for Mice and Rats Amelia R. Adelsperger1, Krista J. Bigiarelli-Nogas2, Irina Toore2, Craig J. Goergen1 1Weldon School of Biomedical Engineering, Purdue University, 2Pre-Clinical Research and Development, Kent Scientific Corporation Here, we present a protocol to more safely and efficiently administer anesthetic gas to mice using a digital, low flow anesthesia system utilizing a syringe-driven direct injection vaporizer.