Georgia Southern University 1 article published in JoVE Cancer Research Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer Shawna Defreitas1, Molly Rowe1, Lily Paculis1, Dongyu Jia1 1Department of Biology, Georgia Southern University Bioinformatics is a useful way to process large-scale datasets. Through the implementation of bioinformatics approaches, researchers can quickly, reliably, and efficiently obtain insightful applications and scientific discoveries. This article demonstrates the utilization of bioinformatics in ovarian cancer research. It also successfully validates bioinformatics findings through experimentation.