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1 article published in JoVE
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The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy
Jennifer Chua1, Nathan A. Fisher2, Shane D. Falcinelli1, David DeShazer1, Arthur M. Friedlander3
1Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, 2Southern Research, 3Headquarters Division, United States Army Medical Research Institute of Infectious Diseases
We present a protocol to utilize the Madagascar hissing cockroach as an alternative non-mammalian animal model to conduct bacterial virulence, pathogenesis, drug toxicity, drug efficacy, and innate immune response studies.
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