Spectrum Health 1 article published in JoVE Medicine Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation Boguslaw Gaweda1,2, Artur Iwasieczko1,2, Manikantam Gaddam3,4, Jared D. Bush3, Brian MacDougal3, Tomasz A. Timek1 1Division of Cardiothoracic Surgery, Spectrum Health, 2Clinical Department of Cardiac Surgery, Clinical District Hospital no 2, Faculty of Medicine, University of Rzeszow, 3Research Department, Meijer Heart and Vascular Institute at Spectrum Health, 4Department of Urology, Stanford University School of Medicine Right ventricular failure and functional tricuspid regurgitation are associated with left-sided heart disease and pulmonary hypertension, which contribute significantly to morbidity and mortality in patients. Establishing a chronic ovine model to study right ventricular failure and functional tricuspid regurgitation will help in understanding their mechanisms, progression, and possible treatments.
