2 articles published in JoVE
Construction of Microdrive Arrays for Chronic Neural Recordings in Awake Behaving Mice Eric H. Chang1, Stephen A. Frattini1, Sergio Robbiati1, Patricio T. Huerta1,2 1Lab of Immune and Neural Networks, Feinstein Institute for Medical Research, North Shore LIJ Health System, 2Department of Molecular Medicine, Hofstra North Shore LIJ School of Medicine The design and assembly of microdrives for in vivo electrophysiological recordings of brain signals from the mouse is described. By attaching microelectrode bundles to sturdy driveable carriers, these techniques allow for long-term and stable neural recordings. The lightweight design allows for unrestricted behavioral performance by the animal following drive implantation.
Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies Wei Li1, Shu Zhu1, Yusong Zhang1, Jianhua Li1, Andrew E. Sama1, Ping Wang1, Haichao Wang1 1The Feinstein Institute for Medical Research, North Shore – LIJ Health System Sepsis refers to a systemic inflammatory response syndrome resulting from a microbial infection, and can be simulated by a surgical technique termed cecal ligation and puncture (CLP). Here we describe a method to use CLP-induced animal model to screen medicinal herbs for therapeutic agents.