2 articles published in JoVE
Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity Odaelys Walwyn*1, Sini Skariah*1, Brian Lynch1, Nathaniel Kim1, Yukari Ueda1, Neal Vohora1, Josh Choe1, Dana G. Mordue1 1Department of Microbiology and Immunology, New York Medical College Forward genetics is a powerful approach to identify genes in intracellular pathogens important for resistance to cell autonomous immunity. The current approach uses innate immune cells, specifically macrophages, to identify novel Toxoplasma gondii genes important for immune evasion.
Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood Mario A. Inchiosa Jr.1,2, Suryanarayana Pothula2, Keshar Kubal1,2, Vajubhai T. Sanchala2, Iris Navarro2 1Department of Pharmacology, New York Medical College, 2Department of Anesthesiology, New York Medical College Demonstration of a rapid quantitative assay of the inhibition of blood coagulation by the low-molecular-weight-heparin, enoxaparin. The contribution of enoxaparin is assessed by removing its influence through digestion with heparinase. A fuller description of the assay is detailed in our published paper.1 The assay still requires clinical confirmation.