New York State Psychiatric Institute

3 articles published in JoVE

• Neuroscience

  
  Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra Garrett Salzman¹, Jocelyn Kim¹, Guillermo Horga*^1,2, Kenneth Wengler*^{1,2 1}New York State Psychiatric Institute, ²Department of Psychiatry, Columbia University This protocol shows how to acquire neuromelanin-sensitive magnetic resonance imaging data of the substantia nigra.

• Immunology and Infection

  
  Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding Benjamin Y. Klein¹, Hadassah Tamir^1,2,3, Muhammad Anwar¹, Robert J. Ludwig¹, Jasmine H. Kaidbey¹, Sara B. Glickstein⁴, Martha G. Welch^{1,2 1}Department of Psychiatry, Columbia University, ²Department of Pathology & Cell Biology, Columbia University Medical Center, ³Department of Psychiatry, Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, ⁴EB Sciences Here, we present a protocol to isolate brain nuclei in the neonatal rat brain in conjunction with first colostrum feeding. This technique allows the study of nutrient insufficiency stress in the brain as modulated by enterocyte signaling.

• Neuroscience

  
  Piezo High Accuracy Surgical Osteal Removal (PHASOR): A Technique for Improved Cranial Window Surgery in Mice Samuel D. Clark¹, Rachel Mikofsky*¹, Jacqueline Lawson*¹, David Sulzer^{1 1}Departments of Psychiatry, Neurology, & Pharmacology, Columbia University Medical Campus Piezoelectric surgery has led to improvements in human maxillofacial and dental surgery. We have developed a protocol to optimize piezoelectric surgery for cranial window surgery in mice.