University at Albany, State University of New York 3 articles published in JoVE Chemistry Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry Ashton D. Lesiak1, Rabi A. Musah1 1Department of Chemistry, University at Albany-SUNY A method for species identification of botanical material by direct analysis in real time-high resolution mass spectrometry and multivariate statistical analysis is presented. Chemistry Flow-pattern Guided Fabrication of High-density Barcode Antibody Microarray Lisa S. Ramirez1,2, Jun Wang1,2 1Department of Chemistry, University at Albany, State University of New York, 2Multiplex Biotechnology Laboratory, Cancer Research Center This protocol outlines the fabrication of a large-scale, multiplexed two-dimensional DNA or antibody array, with potential applications in cell signaling studies and biomarker detection. Bioengineering Nanomanipulation of Single RNA Molecules by Optical Tweezers William Stephenson1, Gorby Wan2, Scott A. Tenenbaum3,4, Pan T. X. Li4,5 1Nanoscale Engineering Graduate Program, College of Nanoscale Science and Engineering, University at Albany, State University of New York, 2Nanoscale Science Undergraduate Program, College of Nanoscale Science and Engineering, University at Albany, State University of New York, 3Nanobioscience Constellation, College of Nanoscale Science and Engineering, University at Albany, State University of New York, 4The RNA Institute, University at Albany, State University of New York, 5Department of Biological Sciences, University at Albany, State University of New York Optical tweezers have been used to study RNA folding by stretching individual molecules from their 5’ and 3’ ends. Here common procedures are described to synthesize RNA molecules for tweezing, calibration of the instrument, and methods to manipulate single molecules.
