Quantitative Imaging Systems LLC 1 article published in JoVE Cancer Research Using Microarrays to Interrogate Microenvironmental Impact on Cellular Phenotypes in Cancer Rebecca Smith1, Kaylyn Devlin1, David Kilburn1, Sean Gross1, Damir Sudar2, Elmar Bucher1, Michel Nederlof2, Mark Dane1, Joe W. Gray1, Laura Heiser1, James E. Korkola1 1Department of Biomedical Engineering, Knight Cancer Institute, Oregon Health and Science University, 2Quantitative Imaging Systems LLC The purpose of the method presented here is to show how microenvironment microarrays (MEMA) can be fabricated and used to interrogate the impact of thousands of simple combinatorial microenvironments on the phenotype of cultured cells.
