Center for the Neural Basis of Cognition

1 article published in JoVE

• Neuroscience

  
  Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging Jeffrey S. Phillips^1,2, Adam S. Greenberg^1,3, John A. Pyles^1,3, Sudhir K. Pathak^1,4, Marlene Behrmann^1,3, Walter Schneider^1,3, Michael J. Tarr^{1,3 1}Center for the Neural Basis of Cognition, ²Department of Psychology, University of Pittsburgh, ³Department of Psychology, Carnegie Mellon University, ⁴Department of Bioengineering, University of Pittsburgh We describe a novel approach for simultaneous analysis of brain function and structure using magnetic resonance imaging (MRI). We assess brain structure with high-resolution diffusion-weighted imaging and white-matter fiber tractography. Unlike standard structural MRI, these techniques allow us to directly relate anatomical connectivity to functional properties of brain networks.