1 article published in JoVE
Zebrafish as a Model to Assess the Teratogenic Potential of Nitrite Vishal Keshari1, Basma Adeeb1, Alison E. Simmons1, Thomas W. Simmons1, Cuong Q. Diep1 1Department of Biology, Indiana University of Pennsylvania Exposure to teratogens may cause birth defects. Zebrafish are useful for determining the teratogenic potential of chemicals. We demonstrate the utility of zebrafish by exposing embryos to various levels of nitrite and also at different times of exposure. We show that nitrite can be toxic and cause severe developmental defects.