Simon Bolivar University

1 article published in JoVE

• Neuroscience

  
  Implantation of Miniosmotic Pumps and Delivery of Tract Tracers to Study Brain Reorganization in Pathophysiological Conditions Eduardo H. Sanchez-Mendoza¹, Jeismar Carballo^1,2,3, Marines Longart², Dirk M. Hermann¹, Thorsten R. Doeppner^{1 1}Department of Neurology, University of Duisburg-Essen, ²Neuroscience Unit, Institute for Advanced Studies (IDEA), ³Department of Cell Biology, Simon Bolivar University In order to study brain reorganization under pathological conditions we used miniosmotic pumps for direct protein delivery into the brain circumventing the blood brain barrier. Tract tracers are then injected to study alterations in brain connectivity under the influence of the protein.