Simon Bolivar University 1 article published in JoVE Neuroscience Implantation of Miniosmotic Pumps and Delivery of Tract Tracers to Study Brain Reorganization in Pathophysiological Conditions Eduardo H. Sanchez-Mendoza1, Jeismar Carballo1,2,3, Marines Longart2, Dirk M. Hermann1, Thorsten R. Doeppner1 1Department of Neurology, University of Duisburg-Essen, 2Neuroscience Unit, Institute for Advanced Studies (IDEA), 3Department of Cell Biology, Simon Bolivar University In order to study brain reorganization under pathological conditions we used miniosmotic pumps for direct protein delivery into the brain circumventing the blood brain barrier. Tract tracers are then injected to study alterations in brain connectivity under the influence of the protein.
