Akihiro Ikeda Department of Medical Genetics University of Wisconsin-Madison Biography Publications Institution JoVE Articles Akihiro Ikeda has not added a biography. If you are Akihiro Ikeda and would like to personalize this page please email our Author Liaison for assistance. Publications Transmembrane Protein 135 Regulates Lipid Homeostasis Through Its Role in Peroxisomal DHA Metabolism Communications Biology. Jan, 2023 | Pubmed ID: 36599953 A Mutation in Transmembrane Protein 135 Impairs Lipid Metabolism in Mouse Eyecups Scientific Reports. Jan, 2022 | Pubmed ID: 35031662 Retinopathy of Prematurity Shows Alterations in Vegfa Isoform Expression Pediatric Research. Jun, 2022 | Pubmed ID: 34285351 The Influence of Mitochondrial Dynamics and Function on Retinal Ganglion Cell Susceptibility in Optic Nerve Disease Cells. Jun, 2021 | Pubmed ID: 34201955 Different Human Immune Lineage Compositions Are Generated in Non-Conditioned NBSGW Mice Depending on HSPC Source Frontiers in Immunology. Month, 2020 | Pubmed ID: 33193358 Modulation of Tmem135 Leads to Retinal Pigmented Epithelium Pathologies in Mice Investigative Ophthalmology & Visual Science. Oct, 2020 | Pubmed ID: 33064130 Metabolic Alterations Caused by the Mutation and Overexpression of the Gene Experimental Biology and Medicine (Maywood, N.J.). Nov, 2020 | Pubmed ID: 32515224 Long-term Evaluation of Retinal Morphology and Function in a Mouse Model of Oxygen-induced Retinopathy Molecular Vision. Month, 2020 | Pubmed ID: 32256029 Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in Mice Genetics. Jan, 2020 | Pubmed ID: 31754016 The Effect of Tmem135 Overexpression on the Mouse Heart PloS One. Month, 2018 | Pubmed ID: 30102730 Metabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes Theranostics. Month, 2017 | Pubmed ID: 28656061 Mouse Mutation Reveals a Mechanism Involving Mitochondrial Dynamics That Leads to Age-dependent Retinal Pathologies ELife. Nov, 2016 | Pubmed ID: 27863209 Syndactyly in a Novel Fras1(rdf) Mutant Results from Interruption of Signals for Interdigital Apoptosis Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2016 | Pubmed ID: 26813283 The Significance of the Discordant Occurrence of Lens Tumors in Humans Versus Other Species Ophthalmology. Sep, 2015 | Pubmed ID: 26130328 A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia Investigative Ophthalmology & Visual Science. Jun, 2015 | Pubmed ID: 26066746 Length Regulation of Mechanosensitive Stereocilia Depends on Very Slow Actin Dynamics and Filament-severing Proteins Nature Communications. Apr, 2015 | Pubmed ID: 25897778 Genetic Basis of Age-dependent Synaptic Abnormalities in the Retina Mammalian Genome : Official Journal of the International Mammalian Genome Society. Feb, 2015 | Pubmed ID: 25273269 Gene Targeting in the Mouse Methods in Molecular Biology (Clifton, N.J.). Month, 2011 | Pubmed ID: 21805269 Mutation in Archain 1, a Subunit of COPI Coatomer Complex, Causes Diluted Coat Color and Purkinje Cell Degeneration PLoS Genetics. May, 2010 | Pubmed ID: 20502676 Serum Response Factor is Essential for the Proper Development of Skin Epithelium Mammalian Genome : Official Journal of the International Mammalian Genome Society. Feb, 2010 | Pubmed ID: 20047077 Defects in Actin Dynamics Lead to an Autoinflammatory Condition Through the Upregulation of CXCL5 PloS One. Jul, 2008 | Pubmed ID: 18628996 Effect of Destrin Mutations on the Gene Expression Profile in Vivo Physiological Genomics. Jun, 2008 | Pubmed ID: 18381839 Carbonic Anhydrase Related Protein 8 Mutation Results in Aberrant Synaptic Morphology and Excitatory Synaptic Function in the Cerebellum Molecular and Cellular Neurosciences. May, 2007 | Pubmed ID: 17376701 Reduced Synaptic Vesicle Density and Aberrant Synaptic Localization Caused by a Splice Site Mutation in the Rs1h Gene Visual Neuroscience. Month, 2006 | Pubmed ID: 17266781 A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration Michael Landowski1,2, Samuel Grindel1, Ying Hao3, Sakae Ikeda1,2, Catherine Bowes Rickman3,4, Akihiro Ikeda1,2 1Department of Medical Genetics, University of Wisconsin-Madison, 2McPherson Eye Research Institute, University of Wisconsin-Madison, 3Department of Ophthalmology, Duke University, 4Department of Cell Biology, Duke University JoVE 64927 Genetica
A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration Michael Landowski1,2, Samuel Grindel1, Ying Hao3, Sakae Ikeda1,2, Catherine Bowes Rickman3,4, Akihiro Ikeda1,2 1Department of Medical Genetics, University of Wisconsin-Madison, 2McPherson Eye Research Institute, University of Wisconsin-Madison, 3Department of Ophthalmology, Duke University, 4Department of Cell Biology, Duke University JoVE 64927 Genetica