Colleen M Novak Department of Biological Sciences Kent State University Biography Publications Institution JoVE Articles Colleen M Novak Colleen M Novak is a Professor of Biological Sciences at Kent State University. She received her undergraduate honors degree from the University of Iowa, and her doctoral degree in Neuroscience from Michigan State University.Dr. Novak’s research focuses on physical activity—how the brain influences the timing and amount of activity, as well as the energetic efficiency of activity. This led to her interest in skeletal muscle thermogenesis and the discovery that exposure to predator threat provokes a strong thermogenic response in muscle. Currently, her laboratory examines the brain, autonomic, and muscle mechanisms underlying this contextual induction of muscle thermogenesis while encouraging the involvement of undergraduate students in research. Publications Differential Weight Loss with Intermittent Fasting or Daily Calorie Restriction in Low- and High-fitness Phenotypes Experimental Physiology. 08, 2021 | Pubmed ID: 34086376 Enhanced Weight and Fat Loss from Long-term Intermittent Fasting in Obesity-prone, Low-fitness Rats Physiology & Behavior. 03, 2021 | Pubmed ID: 33285179 Aerobic Capacity Modulates Adaptive Thermogenesis: Contribution of Non-resting Energy Expenditure Physiology & Behavior. 10, 2020 | Pubmed ID: 32628949 Skeletal Muscle Thermogenesis Induction by Exposure to Predator Odor The Journal of Experimental Biology. 04, 2020 | Pubmed ID: 32165434 Statin Drugs Plus Th1 Cytokines Potentiate Apoptosis and Ras Delocalization in Human Breast Cancer Lines and Combine with Dendritic Cell-Based Immunotherapy to Suppress Tumor Growth in a Mouse Model of HER-2 Disease Vaccines. Feb, 2020 | Pubmed ID: 32041347 Author Correction: Physical Activity, Energy Expenditure, and Defense of Body Weight in Melanocortin 4 Receptor-Deficient Male Rats Scientific Reports. Apr, 2019 | Pubmed ID: 31015504 Caffeine Enhances Activity Thermogenesis and Energy Expenditure in Rats Clinical and Experimental Pharmacology & Physiology. 05, 2019 | Pubmed ID: 30620415 Inherently Lean Rats Have Enhanced Activity and Skeletal Muscle Response to Central Melanocortin Receptors Obesity (Silver Spring, Md.). 05, 2018 | Pubmed ID: 29566460 Suppressed Sympathetic Outflow to Skeletal Muscle, Muscle Thermogenesis, and Activity Energy Expenditure with Calorie Restriction Physiological Reports. Feb, 2017 | Pubmed ID: 28242830 Homeostatic Effects of Exercise and Sleep on Metabolic Processes in Mice with an Overexpressed Skeletal Muscle Clock Biochimie. Jan, 2017 | Pubmed ID: 27916643 Physical Activity, Energy Expenditure, and Defense of Body Weight in Melanocortin 4 Receptor-Deficient Male Rats Scientific Reports. 11, 2016 | Pubmed ID: 27886210 Ventromedial Hypothalamic Melanocortin Receptor Activation: Regulation of Activity Energy Expenditure and Skeletal Muscle Thermogenesis The Journal of Physiology. 09, 2016 | Pubmed ID: 27126579 Contribution of Regional Brain Melanocortin Receptor Subtypes to Elevated Activity Energy Expenditure in Lean, Active Rats Neuroscience. Dec, 2015 | Pubmed ID: 26404873 Interaction of Metabolic Stress with Chronic Mild Stress in Altering Brain Cytokines and Sucrose Preference Behavioral Neuroscience. Jun, 2015 | Pubmed ID: 25914924 Physically Active Rats Lose More Weight During Calorie Restriction Physiology & Behavior. Feb, 2015 | Pubmed ID: 25449411 Leanness and Heightened Nonresting Energy Expenditure: Role of Skeletal Muscle Activity Thermogenesis American Journal of Physiology. Endocrinology and Metabolism. Mar, 2014 | Pubmed ID: 24398400 Enhanced Sympathetic Activity in Mice with Brown Adipose Tissue Transplantation (transBATation) Physiology & Behavior. Feb, 2014 | Pubmed ID: 24291381 Region-specific Differences in Brain Melanocortin Receptors in Rats of the Lean Phenotype Neuroreport. Jul, 2012 | Pubmed ID: 22643233 Smokeless Weight Loss Diabetes. Apr, 2012 | Pubmed ID: 22442297 Loss of FXR Protects Against Diet-induced Obesity and Accelerates Liver Carcinogenesis in Ob/ob Mice Molecular Endocrinology (Baltimore, Md.). Feb, 2012 | Pubmed ID: 22261820 Neuropeptides Controlling Energy Balance: Orexins and Neuromedins Handbook of Experimental Pharmacology. Month, 2012 | Pubmed ID: 22249811 The Use of a Running Wheel to Measure Activity in Rodents: Relationship to Energy Balance, General Activity, and Reward Neuroscience and Biobehavioral Reviews. Mar, 2012 | Pubmed ID: 22230703 Dissociation of Diabetes and Obesity in Mice Lacking Orphan Nuclear Receptor Small Heterodimer Partner Journal of Lipid Research. Dec, 2011 | Pubmed ID: 21949050 Transgenic Expression of Cholesterol 7alpha-hydroxylase in the Liver Prevents High-fat Diet-induced Obesity and Insulin Resistance in Mice Hepatology (Baltimore, Md.). Aug, 2010 | Pubmed ID: 20623580 Spontaneous Activity, Economy of Activity, and Resistance to Diet-induced Obesity in Rats Bred for High Intrinsic Aerobic Capacity Hormones and Behavior. Aug, 2010 | Pubmed ID: 20350549 Measuring Skeletal Muscle Thermogenesis in Mice and Rats Christina A. Watts1, Alexandra Haupt1, Jordan Smith2, Emily Welch3, Aalia Malik3, Roman Giacomino3, Dinah Walter3, Nhlalala Mavundza1, Ashley Shemery1, Heather K. Caldwell1,3, Colleen M. Novak1,3 1School of Biomedical Sciences, Kent State University, 2College of Public Health, Kent State University, 3Department of Biological Sciences, Kent State University JoVE 64264 Comportamento
Measuring Skeletal Muscle Thermogenesis in Mice and Rats Christina A. Watts1, Alexandra Haupt1, Jordan Smith2, Emily Welch3, Aalia Malik3, Roman Giacomino3, Dinah Walter3, Nhlalala Mavundza1, Ashley Shemery1, Heather K. Caldwell1,3, Colleen M. Novak1,3 1School of Biomedical Sciences, Kent State University, 2College of Public Health, Kent State University, 3Department of Biological Sciences, Kent State University JoVE 64264 Comportamento
